4th Call (2016)
Joint Call for Proposals 2016
"Coordination of European funding for infectious diseases research"
This document launches the fourth transnational joint call on human infectious diseases within the framework of the ERA-NET Infect-ERA that aims to coordinate European funding for human infectious diseases research. The submission deadline of the pre-proposal is on March 17, 2016.
The following funding organizations are participating in the call:
- the Austrian Science Fund (FWF), Austria
- the Agency for Innovation by Science and Technology (IWT- Flanders), Belgium
- the Fund for Scientific Research (FNRS), Belgium
- the Research Foundation (FWO- Flanders), Belgium
- the French National Research Agency (ANR), France
- the Federal Ministry of Education and Research (BMBF) represented by Project Management Jülich (PtJ), Germany
- the National Research, Development and Innovation Office (NKFIH), Hungary
- the Department of Biotechnology (DBT), Ministry of Science and Technology, India
- the Chief Scientist Office, Ministry of Health (CSO-MOH), Israel
- the Ministry of Health (MoH), Italy
- the National Centre for Research and Development (NCBR), Poland
- the National Science Centre (NCN), Poland
- the Science and Technology Foundation (FCT), Portugal
- the National Authority for Scientific Research and Innovation (ANCSI), Romania
- the Ministry of Economy and Competitiveness (MINECO), Spain
- the National Institute of Health Carlos III (ISCIII), Spain
The Aim of the call
With this fourth call, Infect-ERA aims to fund transnational and translational research, bringing together basic, applied and technology-driven research approaches of a broad variety of research topics regarding human infectious diseases (ID). This call enables multinational, collaborative research projects that address a specific topic of human ID research.
Consultation to the Scientific Advisory Board of Infect-ERA provided a catalogue of research topics that indicated the current ID research challenges and the tools and methods to address these in the near future. Based on this consultation two main research topics, which are equal in relevance for this call, were identified:
- The host-pathogen interactions, with regard to clinically relevant microbial clones, focused on host susceptibility (e.g., innate immune response, populations at risk, etc.).
- Development of innovative strategies for the diagnostic and treatment of high clinically relevant microbial infections; optimisation of antimicrobial therapy in an individual patient and development of biomarkers to allow individual response prediction.
These two topics include research on bacteria, virus, protozoa and fungi . However proposals with tpivs HIV/AIDS, malaria and tuberculosis are not in the scope the call.
To address the above two topics the proposals could contemplate:
- Identification of host factors that define host susceptibility in regards to infection, disease progression and transmissibility.
- Differences in susceptibility to infections between individuals or inadequate response to infections and/or treatments.
- Host molecular mechanisms that define the competence of the pathogen.
- Development of innovative strategies for the diagnostic and treatment of microbial infections for personalised treatments.
- Identification of biomarkers based on the host-pathogen interaction that allow individual response prediction to shorten antimicrobial treatment courses.
- Identification of rare mutations associated with host susceptibility.
- Individual differences in response to vaccination.
- Development of innovative antimicrobial strategies focused on exploiting the host immune response.
- Development of new methods for rapid determination of drug levels and/or microbial burden, at different body sites and in different bodily fluids, to optimize antimicrobial therapy in an individual patient.
Proposals with topics HIV/AIDS, malaria and tuberculosis are not in the scope of the call.
The proposals should favourably a) show a close cooperation between academic and clinical and/or industrial participants, b) convincingly present the applications (exploitations) of the project results, and c) demonstrate a clear benefit to the public.
General conditions for application
Research proposals may be submitted by:
- higher education institutions,
- non-university public research establishments (including hospitals and clinics),
- commercial companies, in particular small and medium-size enterprises (SMEs),
- researchers according to relevant national regulations.
Only transnational projects will be funded. Each collaborative consortium should have the optimal critical mass to achieve ambitious scientific goals and should clearly show an added value from working together.
Each consortium submitting a proposal must involve:
- a maximum of six partners, however, applicants are encouraged to include partners funded by the following funding organisation: ANCSI (Romania), IWT-Flanders (Belgium), NCBR (Poland), NCN (Poland) and NKIH (Hungary). If such partners are included into the consortium, the maximum number of partners can be increased up to seven
- a maximum of two partners per country
- a minimum of three partners, which must be eligible for the funding organisations of three different countries participating in this call (see the list of funding organisations above)
Non-funded project partners may also be part of the consortia if they are able to clearly demonstrate an added value to the consortium and secure their own funding. However, the coordinator and the majority of partners in a consortium must be eligible for the funding organisations participating in this call. If one of the partners is not eligible the proposal will be rejected without further review.
Each consortium should favourably include participants from both academia and clinics or industry (please note the national regulations).
Each consortium must nominate a project coordinator to represent the consortium, submit the pre-proposal/full proposal, and any further communication with the Joint Call Secretariat. Within a joint proposal, each group leader will be the contact person for the relevant national funding agency.
Young scientists - Part of the available funding is dedicated especially to consortia of young scientists. Each project leader of such consortia must be a “young scientist”, which is defined as having been awarded a PhD or equivalent at least two and a maximum of nine years before the deadline for submission of pre proposals (periods of maternity/paternity leave or military service shall be taken into account).
Submission of proposals will be realised in two steps. In both cases, one joint proposal document (in English) shall be prepared by the project partners of a joint transnational proposal, and must be submitted to the Joint Call Secretariat by the coordinator at www.submission-infect-era.eu.
Potential project partners can be found at http://www.infect-era.eu/collaborations.
The call text and guideline for the applicants is attached on this document as well as the pre-submission - information check form mandatory for Italian partners.
Please note, the guideline for the applicants has been modified on the 20th and 29th on January. The modification is on the link of the Eligibility of costs, types and their caps page 33 from the polish organsation NCN and on the link and caps from the national regulations of National Institute of Heath Juan Carlos III p39-40, respectively.