Sarah Lebeer
Researcher
Address:
Sarah Lebeer
University of Antwerp
Groenenborgerlaan 171
2020 Antwerpen
BelgiumPhone number:
+3232653285
Url of your web site:
Other research topics:
Probiotics
Lactobacilli
Mucosal Immunology
Biotechnology
Other methods/technologies:
* functional analysis: antimicrobial screening, cell culture, ...
* recombinant expression of proteins and mutagenesis of lactobacilli to unravel modes of action
* cell wall biology of probiotics: exopolysaccharides, lipoteichoic acids, peptidoglycan, pili, ...: biochemical and genetic characterization
Suggestions for potential research cooperations:
- antimicrobial activity of lactobacilli/probiotics against various infections (gut, vagina, upper airways, ...)
- study the mode of action of lactobacilli/probiotics: genes, molecules, ...
- study the interaction of probiotics with the mucosal immune system
- study strain-specific cell wall properties of lactobacilli for tailored applications (personalized medicine)
- engineer lactobacilli with therapeutic proteins
- ....
Any further information you consider relevant:
Relevant papers:
* Petrova MI, van den Broek M, Balzarini J, Vanderleyden J, Lebeer S. (2013). Vaginal microbiota and its role in HIV transmission and infection.FEMS Microbiol Rev. 37(5):762-92.
* Lebeer S, Claes IJ, Vanderleyden J. (2012). Anti-inflammatory potential of probiotics: lipoteichoic acid makes a difference. Trends Microbiol. 20(1):5-10.
* Claes IJ, De Keersmaecker SC, Vanderleyden J, Lebeer S. (2011). Mol Nutr Food Res. 55(10):1441-53.
* Lebeer S, Vanderleyden J, De Keersmaecker SC. (2010). Host interactions of probiotic bacterial surface molecules: comparison with commensals and pathogens. Nat Rev Microbiol. 8(3):171-84.
* Lebeer S, Vanderleyden J, De Keersmaecker SC. (2008). Genes and molecules of lactobacilli supporting probiotic action. Microbiol Mol Biol Rev. 72(4):728-64,
Your research topics:
interactions host-pathogen
prevention
treatment
Organism studied by your group:
Bacteria
Virus
Special methods/technologies:
Genetic
Molecular Biology
