Other research topics:
Design and synthesis of new compounds against relevant drug targets, Bioinformatics
Other methods/technologies:
organic synthesis, structure-based design of new compounds, docking, molecular dynamics simulation studies, X-ray crystallography of enzyme/inhibitor complexes
Suggestions for potential research cooperations:
We are an organic chemistry group involved in drug discovery and chemical biology. We are interested in the development of new antimicrobials targeting unexplored targets and new inhibitors of resistance, in particular class D beta-lactamases.
We are also interested in the development of improved diagnostic tools for the detection of resistant bacterial strains to antibiotics. Finally, we are interested in the development of antagonist of quorum sensing as an alternative approach to antibiotics.