Skip to main content Skip to navigation
Home
Infect-ERA
Seven Framework Partner

Search form

  • Home
  • About Infect-ERA
    • Mission
    • Partners
    • Organisation
    • Activities
    • External Advisory Board
  • Joint Calls
    • Previous calls
    • 1st Call (2013)
    • 2nd Call (2014)
    • 3th Call (2015)
    • 4th Call (2016)
  • Related Initiatives
    • National
    • International
  • News & Events
  • Join Infect-ERA
  • Intranet

Dr. Rajesh Mondal

Researcher

Address: 
Dr. Rajesh  Mondal
Molecular Pathogenesis Lab, Department of Microbiology
Dr. Hari Singh Gour Central University
Sagar-  M.P.  470003
India
Phone number: 
+91 9669292564
Any further information you consider relevant: 
As a postdoctoral fellow at Department of Molecular Genetics & Microbiology, College of Medicine, University of Florida, Gainesville (U.S.A.) I had worked on eukaryotic host cell receptors for E. coli common pilus (ECP), a fibrillar structural protein with a potential role in host epithelial cell colonization and may represent a mechanism of adherence of both pathogenic and commensal E.coli. We observed that purified ECP fibers can bind directly to the cell monolayers at the significant level but the cell surface receptors responsible for this binding are still unknown. Since, ECP is a novel adhesion of E. coli (EPEC and EHEC) and acts in concert with the bundle-forming pilus in the formation and stability of the localized microcolonies formed on cultured epithelial cells, we want to understand the mechanism of ECP-mediated adherence and also, how ECP is regulated and assembled. We got some excellent data from this project and submitted an article Jourinal of Bacteriology. Additionally, I was also involved in another project on Type-2 protein secretion system of Pseudomonas aeruginosa. Diverse group of virulent strains of P. aeruginosa, grown under standard and different growth conditions was studied for toxin production and effect on mice (especially for Type-2 protein secretion system). With the help of Two Dimensional Fluorescence Difference Gel Electrophoresis (2-D DIGE) coupled with Mass Spectrometry (MALDI-QTOF), we were able to identify and characterize some type 2 secretary proteins responsible for the early death of mice. I am open to collaborate with the scientist working on Pseudomonas, E coli & Klebsiella spp & also the gram positive ones with Staphylococcus.
Your research topics: 
antimicrobial resistance
diagnostic
interactions host-pathogen
pathogenicity
prevention
treatment
Organism studied by your group: 
Bacteria
Special methods/technologies: 
Genetic
Imaging
Molecular Biology
Screening

Follow Infect-ERA on:

Facebook
LinkedIn
HAS : Hungarian Academy of Sciences
NCN : National Science Centre
FCT : Fundaçãopara a Ciência e a Tecnologia
ISCIII : The National Institute of Health Carlos III
PtJ BMBF logo
French National Research Agency
FWF
MINECO
NCBR : National Centre for Research and Development

© Infect-ERA

  • Administration