Dpto. Microbiologia II. Fac. Farmacia. Pza. Ramon y Cajal s/n
28040 Madrid SpainSpain
+34 91 3941888
+34 91 3941745
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Other research topics:
Budding yeast as a host model for the study of bacterial virulence factors Signal transduction and cell biology in yeast Cell wall as an antifungal target in drug discovery
Post-genomics: whole genome collections, transcriptomics and proteomics
Suggestions for potential research cooperations:
Exploitation of budding yeast genetics to elucidate the function and molecular mechanisms of bacterial virulence factors, with emphasis in those that interfere with cell signaling, cytoskeleton or vesicular traffic.
Any further information you consider relevant:
Examples of our experience in the field can be found in literature: Fernandez-Piñar P, Alemán A, Sondek J, Dohlman HG, Molina M, Martín H. The Salmonella Typhimurium effector SteC inhibits Cdc42-mediated signaling through binding to the exchange factor Cdc24 in Saccharomyces cerevisiae. Mol Biol Cell. 2012 Nov;23(22):4430-43. Rodríguez-Escudero I, Ferrer NL, Rotger R, Cid VJ, Molina M. Interaction of the Salmonella Typhimurium effector protein SopB with host cell Cdc42 is involved in intracellular replication. Mol Microbiol. 2011 80:1220-40. Alemán A, Fernández-Piñar P, Pérez-Núñez D, Rotger R, Martín H, Molina M. A yeast-based genetic screen for identification of pathogenic Salmonella proteins. FEMS Microbiol Lett. 2009 Jun;296(2):167-77.
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