Other methods/technologies:
Medicinal Chemistry, Biophysical methods
Suggestions for potential research cooperations:
Our strength is the rational design and synthesis of small organic antibacterial molecules by medicinal chemistry (e.g. by structure- and ligand-based approaches) followed by their biological evaluation by innovative technologies such as SPR or ITC. In the field of anti-infectives our present target enzymes are the bacterial RNA polymerase as well as the 4-quinolone mediated cell-to-cell communication of P. aeruginosa. In Infect-ERA we aim to contribute with our expertise in MedChem and/or the biological evaluation of the synthesized compounds. We are open to address novel targets.