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Rolf W. Hartmann

Researcher

Address: 
Rolf W.  Hartmann
Helmholtz-Institut für Pharmazeutische Forschung Saarland
Campus Uni
Geb. C2_3
66123  Saarbrücken
Germany
Phone number: 
0681-302-70320
Fax Number: 
0681-302-70347
Url of your web site: 
http://www.helmholtz-hzi.de/de/forschung/forschungsschwerpunkte/neue_wirkstoffe/...
Other methods/technologies: 
Medicinal Chemistry, Biophysical methods
Suggestions for potential research cooperations: 
Our strength is the rational design and synthesis of small organic antibacterial molecules by medicinal chemistry (e.g. by structure- and ligand-based approaches) followed by their biological evaluation by innovative technologies such as SPR or ITC. In the field of anti-infectives our present target enzymes are the bacterial RNA polymerase as well as the 4-quinolone mediated cell-to-cell communication of P. aeruginosa. In Infect-ERA we aim to contribute with our expertise in MedChem and/or the biological evaluation of the synthesized compounds. We are open to address novel targets.
Your research topics: 
antimicrobial resistance
treatment
Organism studied by your group: 
Bacteria
Special methods/technologies: 
Genetic
Molecular Biology
Screening

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